The Ultimate Guide to Getting Rid of Acne

If you try a doctor-prescribed acne regimen for at least a month and you're still experiencing severe breakouts, there's one treatment that's very effective — but it has significant side effects. Isotretinoin (commonly referred to as Accutane, a brand that was taken off the market in 2009) can help with almost all types of acne, though it may be slightly less likely to clear up hormonal acne, says Zeichner. A type of oral retinoid, isotretinoin works by "significantly reducing oil production from your sebaceous glands, which subsequently reduces the amount of P. acnes bacteria on the skin," says Zeichner. It also has an anti-inflammatory effect. (If you're interested in finding out more, ask your doctor about the isotretinoin brands that are available now, such as Claravis, Amnesteem, Myorisan, Zenatane, and Absorica.) Zeichner says that all patients who finish a course of isotretinoin (typically lasting five months, but many physicians recommend a longer treatment plan) will be "significantly better than when they started." For the majority of patients, that can mean 100 percent clear skin. "Approximately 20 percent of patients will need a second course, 5 percent will need a third course, and one percent will need more than three," says Zeichner. But even if you end up in the not-completely-clear camp, the post-treatment breakouts you experience will likely be "much more manageable with traditional treatments, like topicals and oral antibiotics," says Zeichner.

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